How American Cancer Society Uses Machine Learning to Optimize Donor Communication and Boost Fundraising

By: GoBeyond Team
July 27, 2025
3 min read
ACS AI-powered donor communication dashboard

Quick Overview

American Cancer Society applied machine learning to identify optimal communication channels and messaging for donors, significantly enhancing fundraising campaign effectiveness.

American Cancer Society
American Cancer Society
Company Size
~3,000 employees
Revenue Range
$1B+ annual revenue
Primary Challenge
Maximizing donor engagement and fundraising efficiency
Key Metrics

- 400% increase in donation conversion rates
- Optimized fundraising effectiveness

The Problem

Traditional fundraising campaigns lacked data-driven targeting, limiting donor engagement

The Solution

Leveraged machine learning algorithms to analyze donor data and tailor communication strategies

Results

- Dramatic increase in donation conversions
- More efficient use of fundraising resources
- Enhanced donor engagement and retention

“Machine learning has transformed how we connect with donors, maximizing every fundraising dollar.”

Keith Weller, VP Enterprise Technology Services, ACS

Details

Industry
Nonprofit & NGO
Departments
Finance & Accounting
Use Cases
Campaign Management
Tags
Machine Learning
Predictive Modeling
Enhanced Decision-Making
Cost Reduction
AI Tools Used
No items found.
Sources
https://www.linkedin.com/pulse/case-studies-showcasing-how-nonprofits-utilizing-ai-enhance-phillipshttps://cloud.google.com/customers/american-cancer-societyhttps://www.sap.com/sea/insights/viewpoints/how-nonprofits-use-ai-to-find-and-keep-good-donors.html

More Case Studies

See All
How Statworx Deploys AI Models to Optimize Upsell and Cross-Sell Campaigns for Clients
Professional Services & Consulting
How Forbes Uses Quill AI to Generate SEO-Optimized Business and Finance Articles at Scale
Media & Entertainment
How Harbinger Group Developed AI-Powered Onboarding and Learning for a Multinational Investment Bank
Finance & Banking
How DBS Bank Leverages AI and Cloud to Enhance Credit Risk Management, Customer Engagement, and Operational Efficiency
Finance & Banking
How Botkeeper Uses AI to Automate Bookkeeping and Empower Accounting Firms to Scale
Technology & SaaS
How Alibaba Increased Sales and Streamlined Content Creation with AIRec and NLP
Retail & E-commerce

🤖 Chat with AI

Type...